Complete the equation for reductive amination | vedclass

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Question

(A) The process of reductive amination involves the reaction of ammonia with an $\alpha$-keto acid to form an amino acid,facilitated by the enzyme glu

Vedclass · Accepted Answer

$\alpha$-ketoglutaric acid + $NH_4^+$ + $NADPH$

Vedclass · Answer

(A) The process of reductive amination involves the reaction of ammonia with an $\alpha$-keto acid to form an amino acid,facilitated by the enzyme glutamate dehydrogenase and the coenzyme $NAD(P)H$.The primary reaction is:$\alpha$-ketoglutaric acid + $NH_4^+$ + $NAD(P)H \xrightarrow{	ext{Glutamate dehydrogenase}}$ Glutamate + $H_2O$ + $NAD(P)$In this reaction,$\alpha$-ketoglutaric acid acts as the substrate that accepts the ammonium ion to synthesize glutamate.

Complete the equation for reductive amination.

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